产品货号：
Z18463
中文名称：
HTRA2抗体
英文名称：
Anti-HTRA2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HTRA2 Antibody |
| 指标别名 | HtrA serine peptidase 2;HTRA2;OMI;PARK13;PRSS25;Serine protease 25;Serine proteinase OMI |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | HTRA2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | OMI antibody was raised against a peptide corresponding to 16 amino acids near the C-terminus of human Omi.The immunogen is located within amino acids 70 - 120 of OMI. |
| 计算分子量 | 49kDa |
| 成分 | OMI Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | OMI Antibody is Ion exchange chromatography purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Inhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication.Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases.The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs.Recently,a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs.Similar to Smac,Omi possesses a conserved IAP-binding motif,but acts to cleave IAPs to irreversibly inactivate IAPs and promote apoptosis. |
| Uniprot ID | O43464 |
| 基因名全称 | HtrA serine peptidase 2 |
| 蛋白名全称 | HtrA serine peptidase 2 |
| 推荐稀释比 | OMI antibody can be used for detection of OMI by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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